The Yu Lab at the Genome Institute of Singapore (GIS), A*STAR is seeking highly motivated Scientists to join our Chemical Biology team and drive innovative discovery in nucleic acid therapeutics, with a focus on antisense oligonucleotides (ASOs) and RNA-targeted precision medicine.

Our lab specializes in engineering molecular tools to modulate cellular nucleic acids for therapeutic benefit. This position centers on advancing ASO platforms and complementary RNA-targeting strategies to address diseases rooted in genomic dysregulation and currently undruggable pathways. This project aims to develop next-generation ASOs for gene-selective modulation, integrating chemical biology, RNA biology, and functional genomics.

Contract Length: 13-month contract for the first instance.

Key Responsibilities

Nucleic Acid Therapeutics Development