Job Description

Main Purpose of the Job

The Todd Lab, which has recently relocated to the Quadram Institute, will explore diverse sulfur cycling in the human gut. Our projects will apply interdisciplinary research methods to gain fundamental knowledge of the microbes that degrade dietary organosulfur compounds, the pathways and enzymes they utilise, the roles of these pathways, how they are regulated, and their importance to the host microbe, gut microbiome and human health.


The post holder will conduct gut model incubations with diverse organosulfur compounds to determine process rates and the influence of diet and health using metabolomics ( gas chromatography, NMR, LC-MS). They will isolate model gut microbes that cycle diverse dietary sulfur compounds and elucidate their key enzymes and pathways using functional genomics, gene mutagenesis and protein biochemistry. The post will also utilise culture-independent methods, inclu...