At Mayo Clinic, enterprise architecture is not a documentation exercise — it is a strategic lever for how we scale innovation, govern complexity, and deliver on our commitments to patients, clinicians, researchers, and partners. We are seeking a Principal Technologist – Enterprise Architecture Portfolio Lead to serve as a senior leader within the Office of the CTO, shaping and advancing the enterprise architecture agenda across the organization.

Reporting directly to the CTO, this role operates at the center of strategy, board-level commitments, and architectural execution. You will determine which architectural initiatives matter most, how they are framed, when they are sequenced, and how tradeoffs are made across a complex and rapidly evolving portfolio. This is a high-visibility position that requires executive presence, sound judgment, and the ability to engage credibly with senior leaders across business and IT domains.

As the integrator of the enterprise architectu...