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Principal Scientist - RGM Chemistry
Regeneron Pharmaceuticals
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Hawthorne, United States
Location
Hawthorne
Posted
June 17, 2026
Commute
Local Area
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Job Description
We are looking for a visionary Principal Scientist β RGM Chemistry to lead the discovery, development, and optimization of antibody-oligonucleotide conjugation technologies that power next-generation targeted therapeutics. Sitting at the intersection of bioconjugation chemistry, RNA science, and process innovation, you will set scientific strategy, guide a multidisciplinary team, and translate ground breaking concepts into scalable solutions that advance our therapeutic pipeline. Your deep expertise, collaborative attitude, and passion for mentoring will drive breakthrough medicines from bench to preclinical validation and beyond.
**In this role, a typical day might include the following:**
- Designing and completing experiments to refine linker chemistry, payload stability, and delivery efficiency for antibody-oligo conjugates
- Analyzing conjugates with HPLC, LC-MS, and bioassays to ensure purity, identity, and functional potency
- Leading project stand-ups, mentori...
**In this role, a typical day might include the following:**
- Designing and completing experiments to refine linker chemistry, payload stability, and delivery efficiency for antibody-oligo conjugates
- Analyzing conjugates with HPLC, LC-MS, and bioassays to ensure purity, identity, and functional potency
- Leading project stand-ups, mentori...