Vacancy ID: PDS004761

Position Summary/Description:
Postdoctoral fellows will conduct research in the areas of Cancer Epigenomics and Single-Cell Technology development and application to advance cancer research. The Xu Lab investigates heterogeneous transcriptional regulation in cancer through three integrated directions: (1) developing cost-effective single-cell multi-modal technologies to track regulatory evolution across tumor progression; (2) defining epigenetic mechanisms that drive diverse cancer and immune cell behaviors and therapeutic responses, using our innovative approaches such as Paired-TF to link regulatory programs with transcriptional outcomes; and (3) dissecting transcriptional silencer regulation in oncogenesis through large-scale perturbation and single-cell profiling to uncover novel therapeutic targets.

We offer exceptional opportunities for postdocs to take strong leadership and ownership of projects, receive close mentorship, and help shap...