**Job Description**

**_Roles & Responsibilities:_**

Dr. Amaia Lujambio´s research group studies mechanisms of liver cancer initiation and liver cancer maintenance. In particular, we are interested in how genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create vulnerabilities that may be targeted therapeutically. Our research interests involve the establishment of precision in vitro and in vivo systems for the study of liver cancer, as well as the rational use of shRNA and CRISPR libraries to identify drug targets for the disease. We utilize sophisticated mouse models of cancer, RNAi technology, valuable human cancer samples, and genetic and immune profiling as key tools. The ultimate goal is to improve our understanding of liver cancer and to identify novel strategies that can be exploited therapeutically to improve healthspan and longevity.

The project aims at understanding the contribution of different genetic a...