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PhD position: Molecular research on BCL-2 & membrane contact sites
KU Leuven
📍
Leuven, Belgium
Location
Leuven
Posted
June 04, 2026
Commute
Local Area
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Job Description
- Master’s degree in Pharmaceutical Science- Experience in:Mammalian cell culture Fluorescence microscopy of living cells for the analysis of time-resolved calcium signaling and organellar contact sites Immunoblot analyses of cell samples Autophagy and cell death analyses Broader domain of neurodegenerative diseases - Critical thinking and ability to think about experimental design, analyse data rigorously, and solve technical problems proactively.- Rigorous, organized and proactive with a collaborative mindset and enthusiasm to work in an international and interdisciplinary environment.- Proficiency in English, both spoken and written
Anti-apoptotic BCL-2 proteins enable cell survival by preventing mitochondrial BAX/BAK-pore formation and by preventing pro-apoptotic Ca2+-release from the endoplasmic reticulum (ER) (Vogler M et al, Signal Transduct Target Ther, 2025). Hematological cancers are addicted to BCL-2 for their survival by count...