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[50006078-RSE3A] Senior Scientist I, Food & Nutrition
A*STAR - Agency for Science, Technology and Research
📍
singapore, Singapore
Location
singapore
Posted
June 15, 2026
Commute
Local Area
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Job Description
Key Responsibilities
- Lead development and optimisation of GPCR functional assays, including reporter‑based systems (e.g., luciferase, cAMP, calcium, β‑arrestin readouts) suitable for medium‑ to high‑throughput screening.
- Develop new reporter systems for additional functional or phenotypic endpoints beyond GPCR signalling.
- Design, generate, and validate stable or transient mammalian reporter cell lines, including construct design, molecular cloning, and cell line engineering.
- Collaborate with cross‑functional teams (e.g., chemistry, computational biology, screening teams) to support compound evaluation and mechanistic studies.
- Analyse and interpret experimental data, including dose‑response relationships, assay performance metrics, and screening outputs.
- Prepare scientific reports, presentations, and publications, and maintain rigorous documentation of experimental workflows.
- Supervise and train junior sta...